Nashville, Tenn. The chemical nature, biochemistry and physiology of thiamine have been described in detail elsewhere, as has the chemical lesion of the deficiency. In addition to these clearcut, unmistakable functional and structural disorders, there are, apparently, disturbances in the psyche 2 and, possibly, in certain endocrine functions. All Rights Reserved.
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Physicochemical methods excluding HPLC for determining thiamin, riboflavin, niacin, vitamin B 6 , pantothenic acid and vitamin C. High-performance liquid chromatographic methods for the determination of thiamin, riboflavin, niacin, vitamin B 6 folate and vitamin C. Microbiological methods for the determination of the B-group vitamins.
Biospecific methods for the determination of water-soluble vitamins. Appraisal of analytical techniques.
Back Matter Pages Up-regulation and polarized expression of the sodium-ascorbic acid transporter SVCT1 in post-confluent differentiated Caco-2 cells. Scheerger SB, Zempleni J. Expression of oncogenes depends on biotin in human small cell lung cancer cells NCI-H Biotin-dependent expression of the asialoglycoprotein receptor in HepG2 cells.
ISBN 13: 9780412583704
Biotin enhances guanylate cyclase activity. Effect of biotin upon the intracellular level of cGMP and the activity of glucokinase in cultured rat hepatocytes. Watanabe T. Teratogenic effect of biotin deficiency in mice. Tissue abnormalities in newborn rats from biotin-deficient mothers. Texas J. Marginal biotin deficiency is teratogenic in ICR mice. Zempleni J, Mock DM. Marginal biotin deficiency is teratogenic. Sweetman L, Nyhan WL. Inheritable biotin-treatable disorders and associated phenomena.
Impaired biotin status in anticonvulsant therapy.
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The occurrence of free and bound biotin. Biotin status of epileptics. Forbes GM, Forbes A.
Micronutrient status in patients receiving home parenteral nutrition. Biotin deficiency: an unusual complication of parenteral alimentation. Bonjour JP. Vitamins and alcoholism. Riboflavin, VI. Niacin, VII. Pantothenic acid, and VIII. Biotin status assessed longitudinally in pregnant women. Vitamin status in patients with inflammatory bowel disease. Absorption of vitamins from the large intestine. Biotin absorption from the hindgut of the pig. Biotin absorption by distal rat intestine. Biotin uptake by human colonic epithelial NCM cells: a carrier-mediated process shared with pantothenic acid.
Biotinidase deficiency: the possible role of biotinidase in the processing of dietary protein-bound biotin. Fine mapping of the human biotinidase gene and haplotype analysis of five common mutations. Biotin uptake by the human colonic epithelial cells NCM a carrier-mediated process shared with pantothenic acid.
Cellular uptake of biotin: mechanisms and regulation. Said HM, Redha R. Biotin transport in brush border membrane vesicles of rat small intestine.
Biotin transport in human intestine: site of maximum transport and effect of pH. Biotin transport in basolateral membrane vesicles of human intestine. Movement of biotin across the rat intestinal basolateral membrane: studies with membrane vesicles. Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat. Renal Physiol. Cloning, functional expression, gene structure, and chromosomal localization. Molecular mechanism of the intestinal biotin transport process.
Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system. Liver Physiol. Ghosal A, Said HM. Structure—function activity of the human sodium-dependent multivitamin transporter: role of His and His Regulation of intestinal biotin transport in the rat: effect of biotin deficiency and supplementation.
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Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: a study of the hSMVT system. Ontogenesis of the intestinal transport of biotin in the rat. Biotin uptake by the human colonic epithelial cells NCM A carrier-mediated process shared with pantothenic acid.
Peripheral neuropathy of the alcoholic: I, Aetiological role of aneurin and other B-complex vitamins. Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms. Chronic alcohol exposure negatively impacts the physiological and molecular parameters of the renal biotin reabsorption process.
Biotin transport in the human intestine: inhibition by anticonvulsant drugs. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Hereditary folate malabsorption: family report and review of the literature. Evidence for the existence of an electroneutral, pH-dependent, DIDS-sensitive carrier-mediated folate uptake mechanism in the human colonic luminal membrane vesicles. A protein-tyrosine kinase regulated, pH-dependent carrier-mediated uptake system for folate by human normal colonic epithelial cell line NCM Bacterially synthesized folate in rat large intestine is incorporated into host tissue folylpolyglutamates.
Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues. Expert Rev. Sirotnak FM, Tolner B. Carrier-mediated membrane transport of folates in mammalian cells. A novel cDNA restores reduced folate carrier activity and methotraxate sensitivity to transport deficient cells.
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Isolation of hamster cDNA clone coding for a function involved in methotrexate uptake. Human intestinal folate transport: cloning, expression and distribution of complementary RNA. Matherly LH, Hou Z. Structure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter. Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis. Mechanism of folate transport across the human colonic basolateral membrane.
N-linked glycosylation and its impact on the electrophoreticmobility and function of the human proton-coupled folate transporter HsPCFT. Identification of an intestinal heme transporter. Apical membrane targeting and trafficking of the human proton-coupled folate transporter in polarized epithelia.
Intestinal surface acid microclimate in vitro and in vivo in the rat. Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function. The functional roles of the His and His residues in folate and proton translocation mediated by the human proton-coupled folate transporter SLC46A1.